Flavonoids are a major group of antioxidants from various food sources. Excess oxidative load, which may rise from an inadequate supply of flavonoids, has been implicated in the pathogenesis of atherosclerosis, diabetes, and obesity [1,2]. Flavonoids have been shown to enhance cardio-metabolic health in many observational studies and randomized trials [3-5]. Therefore, nutrient supplies favoring pro-oxidant reactions have been considered as promising dietary interventions on cardio-metabolic diseases. As an important source of flavonoids, cocoa products are a potential tasty addition to the armamentarium of nutraceuticals.
Xiaochen Lin MS,Luyu Zhang BA,Alina Li,Lu Wang, MD PhD,Simin Liu MD ScD